Unlock Autism
Archive for the ‘Awareness’ Category
Autism-Spectrum Quotient – AQ
Thursday, June 18th, 2009Psychologist Simon Baron-Cohen and his colleagues at Cambridge’s Autism Research Centre have created the Autism-Spectrum Quotient, or AQ, as a measure of the extent of autistic traits in adults. In the first major trial using the test, the average score in the control group was 16.4. Eighty percent of those diagnosed with autism or a related disorder scored 32 or higher. The test is not a means for making a diagnosis, however, and many who score above 32 and even meet the diagnostic criteria for mild autism or Asperger’s report no difficulty functioning in their everyday lives. You can take the test here.
Why isnt Autism covered by insurance?
Thursday, May 28th, 2009We recently we received this email from Autism Speaks, an organization that is doing great job these days with Autism Awareness. The email speaks of the promise of Autism Treatments being covered by insurance. I say-Why stop at New York State? Why not make it nationwide or worldwide? Governor Plain, Senator McCain since it was part of your platform, why does the support you promised have to end with the election? President Obama and VP Biden, a good idea is a good idea. We can all do more to be supportive of Autism sufferers as we should for anyone suffering with a disease or sickness.
But seriously, can anyone imagine the cost of cancer care, surgery and treatments, not being covered by insurance? Hundreds of thousands of dollars a month or more that I am aware of and I am 1000000% thrilled that it is mostly 100% covered by insurance. That is how it should be in the medical system we have today.
Given the high degree of clinical research data showing how treatments can help benefit Autism sufferers, essentially at every age and stage of life but especially before the age of 3, 7 and 12 years of age. The time has come to get serious about Autism and insurance companies need to step up and begin covering for the treatment of Autism, and government needs to somehow impose on either the insurance comanies or themselves a retro-active refund of coverage or tax credit for prior years spending because $20, $30, $50,000 a year or more on treatment don’t last too long even while making a very healthy six figure income . We insure our health, not against specific diseases- at least that’s what I’ve always thought I was buying into with insurance -does anyone know how that works? Send me a comment.. Does this mean a child with Autism will never be able to be covered by insurance because of a pre-existing condition that has a real chance of being reversed with proper treatment coverage in the first place? Ok you getthe point..
Perhaps the folks I mention above need to watch the movie Sicko by Michael Moore, because it seems to me a lot of people are getting it right when it comes to medical care and it isn’t in the United States of America- which few love more than I.
Here is the email. Get Involved and Take Care.
Imagine a time when autism treatment is covered by insurance. That dream can be a reality for New York state.
Thank you! For 10 years, the autism community has been coming together for Autism Speaks. This year alone over 50,000 strong will unite in Walk Now for Autism Speaks in Long Island, New York City, Rochester, Central New York, Capital Region, Sullivan County, Greater Hudson Valley and Westchester County – raising money and awareness for Autism Speaks, the world’s largest autism advocacy organization in the world. Your time, talent, resources and donations help move ground-breaking research forward and to advance the autism cause. Dollars raised through our Walk Now for Autism Speaks program are the fuel for all of our efforts!
New York State’s time is NOW for insurance legislation. New York has the ability to pass insurance reform this session.
Over the next few weeks we will be in a critical time for this legislation and we will be asking for all of New York state to take action – calling and emailing their senators and assembly members.
“OPT IN” for news about this legislations and action alerts about how you can help. Sign up for Autism Votes today at www.autismvotes.org. If you don’t register you will not receive the action alerts.
Be part of history! Have your voice heard in Albany. Help make it possible for families to get coverage for autism.
The time for this legislation is now – and you can make it happen. You have already taken the first step of being part of our grassroots efforts in New York state by participating or supporting our Walk program. Take the next step and help the almost 130,000 families in New York state who live with autism every day get the coverage they deserve.
UPDATE – It was great to see Sarah Palin marching alongside others at the Autism Walk in Westchester, NY this weekend. Keep it up Sarah, our children need high level partners and supporters in government.
Autism Treatment Acceleration Act – ATAA
Friday, May 15th, 2009Autism Speaks, the nation’s largest autism science and advocacy organization, and Unlock Autism today applauded Representatives Mike Doyle (D-PA), Chris Smith (R-NJ), Eliot Engel (D-NY), and Hank Johnson (D-GA) for their introduction of a House companion bill to the Senate’s Autism Treatment Acceleration Act (ATAA), which was introduced last month by Senators Richard Durbin (D-IL), Robert Casey (D-PA), and Robert Menendez (D-NJ). Like the Senate version, the House version of the ATAA (H.R. 2413) is comprehensive federal legislation that addresses several critical challenges facing the autism community, including increased funding for scientific research, treatment and services. The ATAA incorporates provisions from the Expanding the Promise of Individuals with Autism Act (EPIAA), originally proposed by Representatives Doyle, Smith, Engel, and former-Representative Chip Pickering.
A welcome sign of relief to many who routinely spend $30-$50k on therapy’s – not even considered for reimbursement by insurance companies.
As in the Senate’s ATAA bill, a key section of the House bill requires all insurance companies to provide coverage for the diagnosis and treatment of autism spectrum disorder (ASDs), including coverage of Applied Behavior Analysis (ABA) therapy – a medically-necessary, evidence-based autism treatment. While the number of states that have enacted comprehensive autism insurance reform legislation has grown to ten, most state insurers are still allowed to specifically exclude coverage for these critical services, which can cost upward of $50,000 a year – well beyond the means of most families.
The House version of the bill also addresses the unique needs of adults with ASDs, creating a demonstration project with one-year planning grants and multi-year implementation grants for the provision of service for adults with autism. In addition, it creates the Network for Autism Spectrum Disorders Research and Services aimed at accelerating the dissemination and utilization of critical, new information, moving it from “bench to bedside” as quickly as possible.
The lowdown on BPA and plastic, it aint pretty.
Tuesday, March 31st, 2009Can leaching plastics be involved with the rise in Autism? In m y view ABSOLUTELY! These days everything which was once housed in glass is now in plastic. Plastic water bottles embossed with company logo’s straight from the capital of lead poisining – China, fill almost every corporate portfolio of chatzke giveaways. Its time to rid ourselves of plastics and go back to glass. Rep Charles Schumer of NY has just recently proposed a ban of BPA’s in any baby product, at least someone is aware and doing something about it!
BPA or Bisphenol A is Everywhere – Are We Safe?
BPA otherwise known as Bisphenol A is a compound widely used in the manufacture of plastics and epoxy resins. This
industrial chemical has created quite a stir since 2007 and is still a subject of intense controversy. BPA can be found
in plastics around us and is in the products that we use every day, from DVDs to eyeglasses to mobile phones.
Normally, BPA is harmless, that is, until it gets in contact with food and drinks and leaches out. According to
a report of the National Toxicology Program (NTP) of the U.S. National Institutes of Health (NIH), “the primary
source of exposure to BPA for most people is through the diet…BPA in food and beverages accounts for the majority
of daily human exposure.”
However, not all plastics contain BPA. Plastics are categorized into 7 types according to the recycling process
and the classification codes are located at the bottom of plastic containers. According to NTP, only plastic no. 7,
designated as “other” contains BPA. Incidentally there are other organizations which report that BPA is also found in
plastic no. 3.
Some of the adverse effects that BPA may cause include the following:
BPA is an endocrine disrupting chemical (EDC) that mimics the neurotoxic properties of the hormone estrogen.
According to the Pediatric Environmental Health Specialty Unit (PEHSU) of the Association of Occupational and
Environmental Clinics (AOEC). “BPA has been associated with increases in developmental disorders of the brain and
nervous system in animals. These developmental disorders in animals are like problems such as ADHD (attention deficit
hyper-reactivity disorder) in humans.”
PEHSU reports that “BPA may cause changes in cells in breasts, the uterus, and the prostate which can increase
risk of cancers.” The September 2008 report of NTP suggests that BPA exposure may be linked to prostate and brain
cancer.
The NTP report also says that BPA can cause behavioral problems in fetuses, infants and children. It can induce
early onset of puberty in girls and can cause reproductive disorders.
High BPA levels have been linked to increased risk for cardiovascular disease and diabetes.
It comes as no surprise that these findings have generated a strong anti-BPA movement worldwide. To understand the
controversy behind BPA, let’s look at some of the events that have occurred in the last two years.
March 2007. A class action lawsuit was filed against baby bottle manufacturers on behalf of Californian babies who
may have been adversely affected by BPA.
November 2007. Researchers from the University of Cincinnati published an article in Toxicology Letters
(online edition) reporting that BPA is leaching out of the polycarbonate bottles popularly used as drinking bottles.
This report led to Nalgene plastic bottles taken off the shelves in Canada.
The Environmental Working Group (EWG) tested infant formulas for BPA and detected BPA in some of the most
popular brands. When questioned, 4 out of the top 5 companies admitted using BPA in their packaging.
January 2008. The National Center for Environmental Health of the Centers for Disease Control and Prevention (CDC)
published a paper which reported that BPA was detected in the urine of 92.6% of 2,517 participants during the
2003-2004 National Health and Nutrition Examination Survey (NHNES).
April 2008. Canada announced its plans to ban
BPA-containing bottles. The US FDA established an
agency-wide BPA task force to facilitate cross-agency
review of current research and new information on BPA for
all FDA regulated products.
May 2008. In a health call, “leaders of the Committee on
Energy and Commerce threatened to subpoena the Food and
Drug Administration (FDA) for records the agency used in
determining that the chemical bisphenol A (BPA) was safe
for use in making infant formula liners and other products
intended for infants and children”, according to a report
in the Journal of the American Medical Association (JAMA).
July 2008. The European Food Safety Authority’s AFC Panel
declared that human exposure to BPA is too low to cause any
real harm. According to the panel’s report, the human body
rapidly metabolises and eliminates BPA out of the body.
September 3, 2008
The National Toxicology Program (NTP) issued a report on
BPA, expressing the following concerns: – “some concern”
for effects on the brain, behavior, and prostate gland in
fetuses, infants, and children at current human exposures
to BPA. – “minimal concern” for effects on the mammary
gland and an earlier age for puberty for females, in
fetuses, infants, and children at current human exposures
to BPA. – “negligible concern” that exposure of pregnant
women to BPA will result in fetal or neonatal mortality,
birth defects, or reduced birth weight and growth in their
offspring. – “negligible concern” that exposure to BPA will
cause reproductive effects in non-occupationally exposed
adults and “minimal concern” for workers exposed to higher
levels – in occupational settings. “Some concern”
represents a midpoint in a 5-point scale of concern, with
“serious concern” as the highest and “negligible concern”
as the lowest.
September 2008. Researchers at the University of Exeter
(UK) re-examined the previously mentioned NHNES BPA urine
data. They found that high levels of BPA in the urine were
associated with chronic diseases such as cardiovascular
disorders, diabetes, and kidney problems. The BPA
Subcommittee of the Science Board to the US FDA met on
September 16, 2008 to discuss BPA assessment.
October 2008. Two studies reported research results in mice
exposed to BPA. One study reported that pregnant mice
exposed to BPA suffered from altered the cellular structure
of the breasts. A second study showed that female mice’s
exposure to low-dose BPA during fetal life or adulthood
caused alterations in maternal behaviour.
Researchers at University of Cincinnati report that BPA is
linked to chemotherapy resistance. The study demonstrated
that “BPA does not increase cancer cell proliferation like
DES [cancer-promoting compound called diethylstilbestrol]
does. It’s actually acting by protecting existing cancer
cells from dying in response to anti-cancer drugs, making
chemotherapy significantly less effective.”
The Canadian government announced the drafting of
regulations that will prohibit the import, sale and
advertising of polycarbonate baby bottles that contain BPA.
Based on a review by a subcommittee, the US Food and Drug
Administration (US FDA) stated that “consumers should know
that, based on all available evidence, the present
consensus among regulatory agencies in the United States,
Canada, Europe, and Japan is that current levels of
exposure to BPA through food packaging do not pose an
immediate health risk to the general population, including
infants and babies.” In addition, the US FDA thinks the
Canadian restrictions on BPA are “out of an abundance of
caution.”
January 2009. The US FDA and Health Canada’s Health
Products and Food Branch hosted a meeting of
representatives of U.S and Canadian manufacturers and users
of food packaging materials containing BPA. They discussed
what is to be done to help minimize the levels of BPA in
food. The meeting was also part of FDA’s efforts to assist
the manufacturing industry in its voluntary BPA reduction
efforts.
So what can we do to protect ourselves from BPA?
Recommendations from PEHSU – Avoid plastics with symbol # 3
(PVC or polyvinyl), symbol # 6 (PS or polystyrene foam) and
symbol #. Do not microwave food/beverages in plastic. Do
not microwave or heat plastic cling wraps. Do not place
plastics in the dishwasher. If using hard polycarbonate
plastics (water bottles/baby bottles/sippy cups), do not
use for warm/hot liquids. Use safe alternatives such as
glass or polyethylene plastic (symbol #1). Avoid canned
foods when possible (BPA may be used in can linings). Look
for labels on products that say “phthalate-free” or
“BPA-free”.
Recommendations from the Center for Science in the Public
Interest (CSPI): Avoid plastic containers made of
polycarbonate. Any bottle or container made of
polycarbonate has the recycling No. 7 on the bottom. When
possible, prepare or store food—especially hot foods
and liquids—in glass, porcelain, or stainless steel
dishes or containers. If you have polycarbonate plastic
food containers, don’t microwave them. The plastic is more
likely to break down and release BPA when it’s repeatedly
heated to high temperatures. Don’t wash polycarbonate
plastic containers in the dishwasher. The detergent may
break down the plastic, which could release BPA. Use infant
formula bottles that are made of glass or BPA-free plastic.
BornFree (newbornfree.com) is one of many companies that
make them. When you can, replace canned foods with foods
that are fresh, frozen, or packaged in aseptic
(shelf-stable) boxes. At least one manufacturer—Eden
Foods—lines its cans with a BPA alternative made from
plant extracts. A good alternative to polycarbonate is
polyethylene terephthalate (PETE), which has the recycling
No. 1 on the bottom. Avoid older versions of Delton dental
sealant…Most dental sealants are free of BPA. However,
older Delton sealants contain a compound that breaks down
into BPA, mostly during the first day after it comes into
contact with saliva.
—————————————————-
The article BPA or Bisphenol A is Everywhere – Are We Safe?
may be found in it’s entirety with references and links on
http://HealthWorldNet.com .
Spider Man Saves the Day
Tuesday, March 24th, 2009I believe it is safe to say this could work with any kid who loves Spidey, not just a person with Autism.
BANGKOK (AFP) – A Thai fireman turned superhero when he dressed up as comic-book character Spider-Man to coax a frightened eight-year-old from a balcony, police said Tuesday.
Teachers at a special needs school in Bangkok alerted authorities on Monday when an autistic pupil, scared of attending his first day at school, sat out on the third-floor ledge and refused to come inside, a police sergeant told AFP.
Despite teachers’ efforts to beckon the boy inside, he refused to budge until his mother mentioned her son’s love of superheroes, prompting fireman Sonchai Yoosabai to take a novel approach to the problem.
The rescuer dashed back to his fire station and made a quick change into a Spider-Man costume before returning to the boy, he said.
“I told him Spider-Man is here to rescue you, no monsters are going to attack you and I told him to walk slowly towards me as running could be dangerous,” Somchai told local television.
The young boy immediately stood up and walked into his rescuer’s arms, police said.
Somchai said he keeps the Spider-Man costume and an outfit of Japanese television character Ultraman at the station in order to liven up school fire drills.
Do Vaccines Cause Autism, Apparently not
Thursday, February 12th, 2009Just saw this report, could vaccines be the great dead end towards finding a cure? It seems an awful lot of money has been spent and many pointing fingers..
WASHINGTON (Reuters) – A special U.S. court ruled against three families on Thursday who claimed vaccines caused their children’s autism.
The Vaccine Court Omnibus Autism Proceeding ruled against the parents of Michelle Cedillo, Colten Snyder and William Yates Hazlehurst, who had claimed that a measles, mumps and rubella vaccines had combined with other vaccine ingredients to damage the three children.
“I conclude that the petitioners have not demonstrated that they are entitled to an award on Michelle’s behalf,” Special Master George Hastings, a former tax claims expert at the Department of Justice, wrote in the Cedillo ruling.
The families sought payment under the National Vaccine Injury Compensation Program, a no-fault system that has a $2.5 billion fund built up from a 75-cent-per-dose tax on vaccines.
No judges but instead three “special masters” heard the three test cases representing thousand of other petitioners.
They asked whether a combination vaccine for measles, mumps and rubella, or MMR, plus a mercury-containing preservative called thimerosal, caused the children’s symptoms.
Update on the 2009 Peanut Butter Recall
Thursday, February 5th, 2009Here is an update on the recent Salmonella Poisoning affecting the Peanut Butter Industry. I wonder how this will effect those allergic to anything with Peanuts?
Recently, the Peanut Corporation of America (PCA) issued a
recall of peanut butter manufactured from its Blakely,
Georgia production plant after reports from nearly 500
individuals who had developed salmonella poisoning because
of infected peanut butter flooded health officials.
The contaminated peanut butter has caused at least seven
known deaths and is expected to continue to affect
individuals across the United States as the contaminated
peanut butter has been used in several varying products
ranging from crackers to cookies. Individuals are advised
to avoid consumption of peanut butter containing products.
However, those who have already been affected by the peanut
butter recall may want to locate an experienced attorney
who can provide assistance in the development of a peanut
butter recall lawsuit, which may result in compensation of
monetary means for a victim of the dangerous and
life-threatening recall.
What is Salmonella?
Salmonella poisoning occurs because of an infection known
as salmonellosis, which is derived from the bacteria
salmonella. According to the Centers for Disease Control
and Prevention (CDC) “salmonella is actually a group of
bacteria that can cause diarrheal illness in humans.”
According to the CDC, “approximately 40,000 cases of
salmonellosis are reported in the United States” each year,
however, “because many milder cases are not diagnosed or
reported, the actual number of infections may be thirty or
more times greater.” It is common that children are to
develop salmonella more frequently than adults, however,
individuals of any age can become infected with the
disease, which has been associated with to nearly 400
fatalities each year.
Salmonella Causes
Individuals who develop salmonella usually develop the
infection by consuming foods that have been “contaminated”
with animal feces. Most commonly, the foods that can be
affected include the following, according to the CDC:
* beef
* poultry
* milk
* eggs
While contaminated foods are often of animal origin, nearly
any food product can become infected with the bacteria
including vegetables and fruits, especially amoang foods
with undercooked meats or eggs, such as the following:
* homemade Hollandaise sauce
* Caesar and other homemade salad dressings
* tiramisu
* homemade ice creams
* cookie dough
* frostings
* mayonnaise
* raw or unpasteurized milk/dairy products
Additionally, if an individual handles any of the following
animals, he or she may become infected with the bacteria,
even if an animal appears healthy and normal:
* chicks/chickens
* young birds
* turtles
* lizards
* snakes
* pets of any kind
While salmonella can be killed by washing hands, if an
individual does not properly wash hands or
cross-contaminates utensils, such as knives or cutting
boards, they may be at risk for exposing others to
salmonella poisoning.
Those who have suffered from salmonella may be subject to
receiving monetary compensation for the pain they have
endured due to foods containing salmonella. It is important
to discuss a salmonella case with an experienced law firm
to learn about the details of a potential salmonella
poisoning lawsuit.
——————————
To learn more about the controversy surrounding the peanut
butter recall, visit http://peanut-butter.legalview.info/ .
ATTN New Yorkers: State Assembly to Hold Hearing on Autism Services
Friday, December 12th, 2008
The Assembly Standing Committee on Insurance will hold a Public Hearing regarding the Treatment of Autism Spectrum Disorder on Thursday, December 18, 2008 at 10am to discuss the management of Autism in New York State with specific attention to early diagnosis and intervention. The meeting will be held in Chancellor’s Hall in the State Education Building at 89 Washington Avenue (use the entrance on Hawk Street) in Albany.
During the hearing, testimony will be presented to evaluate programs and treatment options that already exist in this state for children with ASD, as well as evaluating what can be done to improve their living standards and assist families and caregivers with their many burdens, including financial, of dealing with Autism Spectrum Disorders.
This is the perfect opportunity for our community to demonstrate to the NYS Assembly that the autism community is dedicated to these issues – enough to show up in the winter cold and at holiday time – it’s just that important!
HOW CAN YOU HELP?
1) DRIVE TO ALBANY! This is a great chance for our community to demonstrate how important this issue is moving forward with our physical presence. Please plan on attending. We want to PACK THE ROOM!
2) FORWARD THIS EMAIL FAR AND WIDE! Again, we want to pack the room so send this to anyone that you think could attend: neighbors, coworkers, family members, your child’s therapists!
3) REGISTER TO STAY INFORMED! If you haven’t signed up already, please visit the Autism Votes website and sign up to receive action alerts as we move forward on autism insurance reform in the state of New York!
Thank you for your help in this effort,
Your New York State Chapter Advocacy Chairs:
Jim Fahey, CAC – All New York State
NewYorkCAC@autismspeaks.org
Julie Rotunno, CAC – New York City
NYCCAC@autismspeaks.org
Julie Buick, CAC – Rochester
RochesterCAC@autismspeaks.org
Sharan DePalma, CAC – Westchester
WestchesterCAC@autismspeaks.org
When Myelin Is The Cause, Might Nicotine Be the Cure?
Monday, November 24th, 2008The development, maintenance, and repair of myelin is the single most important factor affecting cognition and behavior, according to a UCLA neurology professor who has collected extensive data on the nerve insulator. In an article to be published in an upcoming issue of Biological Psychiatry, George Bartzokis, MD, asserts that myelin may be the universal cause or contributor to a wide range of neuropsychological brain disorders, from autism to Alzheimer’s disease. Dr. Bartzokis, who directs the UCLA Memory Disorders and Alzheimer’s Disease Clinic in Los Angeles, suggests that using noninvasive imaging technology to view the miles of myelin in the brain as it grows and breaks down throughout a human life cycle may offer insights leading to the development of new treatments for brain disorders. Nicotine, which studies have suggested enhances the growth and maintenance of myelin, could be one such novel treatment.
In some of the first research to approach brain disorders from a myelin-centered point of view, Dr. Bartzokis studied the effects of cholinergic treatments, including acetylcholinesterase inhibitors (AChEIs) that are used to improve a neuron’s synaptic signaling in people with diseases such as Alzheimer’s. Some data suggest that such treatments may even modify or slow the progression of Alzheimer’s as well as other diseases.
Nicotine, Age, and Disease
Dr. Bartzokis hypothesizes that cholinergic stimulation at neuronal synapses affects the myelination process throughout brain development in the course of a human’s lifetime.He found in clinical trials that cholinergic treatment protects brain cells, while postmortem and imaging data have shown cholinergic receptor changes during brain development and degeneration. Trials have also revealed epidemiologic evidence that nicotine from tobacco may have a protective effect on degenerative diseases of old age and younger psychiatric populations. Cholinergic treatments have also shown efficacy in the aging process and age-related neurodegenerative diseases such as Alzheimer’s disease, as well as some neurodegenerative diseases like autism and ADHD.
According to Dr. Bartzokis, myelination development resembles an inverted “U” over the course of a lifetime, with increasing myelin development peaking in middle age and breaking down and declining in later years. Following the analogy of the Internet, Dr. Bartzokis says the “connectivity” provided by myelination increases speed by 10-fold and decreases refractory time by 34-fold. Thus, myelination increases the “bandwidth,” or processing capacity, of our brain’s Internet by 340-fold and is “indispensable for developing our uniquely elaborate higher cognitive functions.”
Different cortical regions myelinate at different ages, with later-myelinating oligodendrocytes growing increasingly more complex as we age. Irregular development during the most complex stages of the myelination process contributes to several of the neuropsychiatric disorders that tend to manifest in the early years. These disorders—eg, autism, ADHD, schizophrenia, mood disorders, addictions—are defined by overlapping cognitive and behavioral symptom clusters.
According to Dr. Bartzokis, healthy individuals with normal myelin development typically lose 45% of their myelinated fiber length when they reach the degeneration phase in adulthood. This change in the brain may cause progressive losses of memory and cognitive functions, as well as mild to severe behavioral changes.
The loss of myelin and its components such as sulfatide, myelin basic protein, and cholesterol begins early in the development of Alzheimer’s disease, well before diagnosis of dementia or mild cognitive impairment. The myelin breakdown process is further modified by risk factors such as the presence of APOE ε4 or environmental factors such as a head trauma.
Nicotine’s Effect on Myelination and Repair
Recent research has unveiled some surprising findings on the influence of nicotine on myelination and the aging process. Direct nicotinic stimulation associated with smoking has been shown to increase nicotinic receptors in the late myelinating frontal and temporal intracortical regions. Unlike most agonists, nicotine causes an up-regulation of its receptors and has been shown to accelerate brain function recovery when white matter is damaged.
Nicotine dependence is common among people with psychiatric disorders. Some researchers have suggested the high prevalence of nicotine use among the psychiatric population represents an unconscious effort to “self-medicate.” Research on proteins has suggested that nicotine may marginally increase the expression of myelin proteins; other addictive drugs (eg, cocaine, alcohol) along with developmental diseases (eg, schizophrenia, bipolar disorder, depression) show a decrease of these proteins.
Other research has found an association between nicotinic stimulation and protective effects in schizophrenia and autism, where cortical myelination deficits have been documented. While nicotine has well-known negative effects on overall health, smoking during later years is also associated with a reduced likelihood of the development of degenerative conditions like Alzheimer’s and Parkinson’s diseases. Using the myelin-centered model, the apparent beneficial aspects of smoking on brain disorders can be attributed to nicotine’s stimulation of oligodendrocyte precursors. Dr. Bartzokis believes that nicotine, delivered through a patch, not through smoking cigarettes, should be studied for its efficacy in promoting the growth and maintenance of myelin, and that AChEIs “deserve much closer scrutiny” as a therapy for the prevention of both developmental and degenerative brain disorders.
—Kathlyn Stone http://www.neuropsychiatryreviews.com/07jan/myelin.html







